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Viggo - Our Cat


Menotti80

As some people here might know, we have had a pretty bad string of luck when it comes to our animals in the past 2 years.

 

Besides having to put our beagle down last year, our first cat died on the operating table at my fiance's work 2 summers ago during a routine procedure.

 

We got a new cat a few months later, and is as still our baby. This weekend, we noticed changes in his behavior, and Jackie ended up bring him into work to run a few tests and to get him some fluids.

 

This morning, he took a turn for the worse, and it currently fighting for his life. I was just there to visit him, and although it doesn't look good, we are still hoping he can pull through.

 

Any thoughts or prayers would be much appreciated. Thanks.

 

 

 

edit: changed title

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update:

 

it's not looking good. he's still running a fever (between 103 and 106), and his liver is failing. the antibiotic they were using hasn't worked. they are trying a new one today, and will put him on steroids tomorrow (assuming he doesn't improve today), which may help save the liver. if that doesn't work, they will biopsy the liver, but it would be pretty much hopeless at that point...

 

 

thanks again for your support. you guys are awesome.

 

http://images.yuku.com/image/jpg/31d257a9da8cf44918cbd93ae860e2ce2ec5ec9.jpg

 

 

http://images.yuku.com/image/jpg/7df25de90a8a148d1d0b16a11792b5654963645.jpg

 

 

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I'm sorry to hear this. Poor fella. Good luck!

 

Just a few thoughts. Maybe there is a pattern here? Could your husband accidently be bringing germs home with him from work? Highly unlikely, just thought I would mention it. Another thing I thought about was possible exposure to heavy metals, mold, or other poisonous reagents. Heavy metal exposure likely would occur either through exposure in the local top soil or the local water. Heavy metals are found in high numbers in older houses too. Old paint, insulation, countertops, masonery, etc, could contain lead among other things. Mold could come in contact with pets just about anywhere; basement, outdoors/rotting trees/stagnant water, water/food dishes or storage, etc.

 

I hope this post doesn't come off as an accusation.....I just thought it might help find a cause.

 

Good luck Viggo!

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just to clerify, my fiance (soon to be wife) works at the animal hospital, not husband. i will be the husband... http://forum.brewerfan.net/images/smilies/smile.gif

 

but to answer the things you brought up in your post, most of those were possibilities that the doctors did look at. but viggo is an inside cat only, so the threat of something from outside being the problem wasn't likely, but they did run tests to make sure.

 

they also did check for exposure to harmful things in our surroundings, but those also turned out to not be an issue. but thank you for all of those suggestions. i actually brought up the possibility of flowers as being a potential hazard. jackie brought in some tulips from our garden to display in the house last week, so i thought maybe he ate one of them or something. but it turns out only the bulb and some other part of the flower can be harmful, but they checked anyways.

 

they think they know what is the problem. i will try to get the name and description of it, but i know they think it's a pretty uncommon disease/condition that only a few breeds of cats can get (persian is one of them), and it's only found in males. but as of today, hey are giving him steroids to try to repair the liver.

 

keeping my fingers crossed...

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this is what they think he has:

 

http://www.petplace.com/cats/cholangiohepatitis/page1.aspx

 

he had a lot of the symptoms (he does have the ones listed below), but i am not sure which form they think he has. (i think suppurative)

What to Watch For:

Fever

Loss of appetite

Dehydration

Lethargy, collapse

right now, they are going to ultrasound his liver again to see if the ducts are clearing at all. if they are, that would be a wonderful sign. thanks again everyone!

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http://images.yuku.com/image/jpg/7df25de90a8a148d1d0b16a11792b5654963645.jpg
That's his "You got nothin' on ME, cholangiohepatitis! You're going DOWN!" look. Hope he pulls through.

 

Edit: also, he's adorable. That gray and white coat is fantastic!

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The pics make me feel sad......I am pulling for the little guy. The worst part of owning an animal is when thinigs like this happen and you feel so helpless. I am glad you happen to be very close to a vet... http://forum.brewerfan.net/images/smilies/smile.gif .....

 

He is a good looking cat. And a fighter

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i feel like i've been hit with a ton of bricks. he seemed to be getting better last night. walking around, seemingly in a better mood. we were almost sure today was going to be the day where it all turned around and he would start to get better. i just got a call that he now has fluids in his lungs, and that is heart is now slightly enlarged.

 

now the fear is FIP. that meant nothing to me a week ago, but became something that i never wanted to hear once i learned what it was. and the bottom line is no cure. they are giving him something right now that might help get rid of the fluid, which is pretty much our last shot. this should be all but decided one way or another this morning. a 4th round of blood work would confirm after this latest try at treatment.

 

 

What is FIP?

 

Feline infectious peritonitis (FIP) is a viral disease of cats caused by certain strains of a virus called the feline coronavirus. Most strains of feline coronavirus are avirulent, which means that they do not cause disease, and are referred to as feline enteric coronavirus. Cats infected with a feline coronavirus generally do not show any symptoms during the initial viral infection, and an immune response occurs with the development of antiviral antibodies. In a small percent of infected cats (5 to 10 percent), either by a mutation of the virus or by an aberration of the immune response, the infection progresses into clinical FIP. The virus is then referred to as feline infectious peritonitis virus (FIPV). With the assistance of the antibodies that are supposed to protect the cat, white blood cells are infected with virus, and these cells then transport the virus throughout the cat's body. An intense inflammatory reaction occurs around vessels in the tissues where these infected cells locate, often in the abdomen, kidney, or brain. It is this interaction between the body's own immune system and the virus that is responsible for the disease. Once a cat develops clinical FIP involving one or many systems of the cat's body, the disease is progressive and is almost always fatal. The way clinical FIP develops as an immune-mediated disease is unique, unlike any other viral disease of animals or humans.

 

Is my cat at risk for developing FIP?

 

Any cat that carries any coronavirus is potentially at risk for developing FIP. However, cats with weak immune systems are most likely to develop the disease, including kittens, cats already infected with feline leukemia virus (FeLV), and geriatric cats. Most cats that develop FIP are under two years of age, but cats of any age may develop the disease.

 

FIP is not a highly contagious disease, since by the time the cat develops clinical disease only a small amount of virus is being shed. Feline coronavirus can be found in large quantities in the saliva and feces of cats during the acute infection, and to a lesser extent in recovered or carrier cats, so it can be transmitted through cat-to-cat contact and exposure to feces. The virus can also live in the environment for several weeks. The most common transmission of feline coronavirus occurs when infected female cats pass along the virus to their kittens, usually when the kittens are between five and eight weeks of age.

 

FIP is relatively uncommon in the general cat population. However, the disease rate is much higher in multiple-cat populations, such as some shelters and catteries. FIP has also been shown to be more common in certain breeds, but the research is still unclear as to whether these breeds are more susceptible because of their genetics or whether they are exposed to feline coronavirus more often because many of them come from catteries.

 

What are the symptoms of FIP?

 

Cats that have been initially exposed to the feline coronavirus usually show no obvious symptoms. Some cats may show mild upper respiratory symptoms such as sneezing, watery eyes, and nasal discharge. Other cats may experience a mild intestinal disease and show symptoms such as diarrhea. Only a small percentage of cats that are exposed to the feline coronavirus develop FIP-and this can occur weeks, months, or even years after initial exposure.

 

In cats that develop FIP, the symptoms can appear to be sudden since cats have an amazing ability to mask disease until they are in a crisis state. Once symptoms develop, often there is increasing severity over the course of several weeks, ending in death. Generally, these cats first develop nonspecific symptoms such as loss of appetite, weight loss, depression, rough hair coat, and fever.

 

There are two major forms of FIP, an effusive, or "wet" form, and a noneffusive, or "dry" form. Generally, cats will exhibit the signs of the noneffusive form FIP more slowly than the effusive form. Symptoms generally include chronic weight loss, depression, anemia, and a persistent fever that does not respond to antibiotic therapy.

 

The effusive form of FIP is characterized by an accumulation of fluid in the abdomen, or less commonly in the chest. Early in the disease, the cat may exhibit similar symptoms to the dry form, including weight loss, fever, loss of appetite, and lethargy. The wet form of the disease often progresses rapidly, and the cat may quickly appear pot-bellied due to fluid accumulation in the abdomen. When the fluid accumulation becomes excessive, it may become difficult for the cat to breathe normally.

 

FIP can be difficult to diagnose because each cat can display different symptoms that are similar to those of many other diseases.

 

Can my cat be tested for FIP?

 

One of the most difficult aspects of FIP is that there is no simple diagnostic test. The ELISA, IFA, and virus-neutralization tests detect the presence of coronavirus antibodies in a cat, but these tests cannot differentiate between the various strains of feline coronavirus. A positive result means only that the cat has had a prior exposure to coronavirus, but not necessarily one that causes FIP.

 

The number that is reported from these tests is called an antibody titer. Low titers indicate a small amount of coronavirus antibodies, while high titers indicate much greater amounts of antibodies. A healthy cat with a high titer, however, is not necessarily more likely to develop FIP or be a carrier of an FIP-causing coronavirus than a cat with a low titer. A cat with a high titer is also not necessarily protected against developing FIP in the future.

 

Other tests have been developed that can detect parts of the virus itself. The immunoperoxidase test detects virus-infected cells in the tissue, but a biopsy of affected tissue is necessary for evaluation. Another antigen test uses polymerase chain reaction (PCR) to detect viral genetic material in tissue or body fluid. Although this test shows promise, PCR is presently only capable of detecting coronaviruses in general, not necessarily those that cause FIP.

 

To date, there is no way to screen healthy cats for the risk of developing FIP, and the only way to definitively diagnose FIP is by biopsy, or examination of tissues at autopsy. Generally, veterinarians may rely on a presumptive diagnosis, which can be made with a relatively high degree of confidence by evaluation of the cat's history, presenting symptoms, examination of fluid if it is present, and the results of supporting laboratory tests including a positive coronavirus antibody titer.

 

Can FIP be treated?

 

Unfortunately, there is no known cure or effective treatment for FIP at this time. Some treatments may induce short-term remissions in a small percentage of cats; however, FIP is a fatal disease. Treatment is generally aimed at supportive care, such as good nursing care and nutrition, and alleviating the inflammatory response of the disease. Cats with FIP are often treated with corticosteroids, cytotoxic drugs, and antibiotics. Supportive care may also include fluid therapy, draining accumulated fluids, and blood transfusions.

 

Research is ongoing to find other immunosuppressive drugs that may slow down the progress of the disease. Attempts are also being made to find antiviral drugs that will prevent or slow down the replication of the virus. One promising approach currently being studied combines both an antiviral agent and an immune response modifier.

 

Can I protect my cat from getting FIP?

 

In multiple cat environments, keeping cats as healthy as possible and minimizing exposure to infectious agents decreases the likelihood of cats developing FIP. Litter boxes should be kept clean and located away from food and water dishes. Litter should be cleansed of feces daily, and the box should be thoroughly cleaned and disinfected regularly. Newly acquired cats and any cats that are suspected of being infected should be separated from other cats. Preventing overcrowding, keeping cats current on vaccinations, and providing proper nutrition can also help decrease the occurrence of FIP in groups of cats.

 

There is only one licensed FIP vaccine available; however, this vaccine has minimal if any effectiveness in preventing FIP, and it is not generally recommended by the American Association of Feline Practitioners Feline Vaccine Advisory Panel. Primucell FIP, produced by Pfizer Animal Health, is a temperature-sensitive, modified-live virus vaccine that is given as an intranasal vaccine, and is licensed for use in cats at least 16 weeks of age. The vaccine appears to be safe, but the risks and benefits of vaccination should be weighed carefully. Cat owners should consult their veterinarian to help them decide if their cat should be vaccinated.

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